FGF12 抗体 (AA 1-243) (FL550)
Quick Overview for FGF12 抗体 (AA 1-243) (FL550) (ABIN7595538)
抗原
See all FGF12 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-243
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原理
- Anti-FGF12/FHF1 Antibody FL550 Conjugate
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特异性
- Recognizes FGF12b/FHF1bNo off-targets reported for FGF11/FHF3, FGF13/FHF2 or FGF14/FHF4
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-FGF12/FHF1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N94/17. It detects human, mouse, and rat FGF12/FHF1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Manufacturer Comment: We produce our FGF12/FHF1 mouse monoclonal primary antibody from hybridoma clone N94/17. It is great in IHC, ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 1-243 (full-length) of human FGF12a (accession number P61328) produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- FGF12 (Fibroblast Growth Factor 12 (FGF12))
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别名
- FHF1
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背景
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Synonyms: Fibroblast growth factor 12 (FGF-12) (Fibroblast growth factor homologous factor 1) (FHF-1) (Myocyte-activating factor)
Target Description: Fibroblast growth factor 12, FHF1 or FGF12 is encoded by the gene FGF12. FHF1 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF12 has been found to be expressed in the brain, eye and testis. Diseases associated with FGF12 include Early Infantile Epileptic Encephalopathy, Ebstein anomaly and Autosomal Dominant Deafness.
Gene Name Alternatives: FGF12 FGF12B FHF1
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分子量
- 27 kDa
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途径
- Negative Regulation of Transporter Activity
抗原
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