DLG1 抗体 (AA 1-104) (FL490)
Quick Overview for DLG1 抗体 (AA 1-104) (FL490) (ABIN7595518)
抗原
See all DLG1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-104
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原理
- Anti-SAP97 Antibody FL490 Conjugate
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特异性
- No off-targets reported for PSD-95, Chapsyn-110 and SAP102 expressed in transfected cells
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-SAP97 mouse monoclonal primary antibody is produced in-house from hybridoma clone K64/15. It is KO validated, detects human, mouse, and rat SAP97, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Manufacturer Comment: We produce our SAP97 mouse monoclonal primary antibody from hybridoma clone K64/15. It is great in IHC, ICC and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.
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纯度
- > 90 % specific antibody
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免疫原
- Fusion protein amino acids 1-104 (N-terminus) of rat SAP97 (accession number Q62696) produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.09 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 12 months
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- DLG1 (Discs, Large Homolog 1 (DLG1))
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别名
- SAP97
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背景
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Synonyms: Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Target Description: Synapse-associated protein 97, Discs Large MAGUK Scaffold Protein 1 or SAP97 is encoded by the gene DLG1. SAP97 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. It is a multi-domain scaffolding protein which serves to recruit receptors channels and other signaling molecules to the plasma membrane. SAP97 is expressed in heart, lung, epithelial cells and brain. SAP97 may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Diseases associated with DLG1 include Mayer-Rokitansky-Kuster-Hauser Syndrome and Depression.
Gene Name Alternatives: Dlg1 Dlgh1
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分子量
- 130 kDa
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途径
- Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response
抗原
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