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Neuroligin 1 抗体 (AA 718-843) (FL490)

This anti-Neuroligin 1 antibody is a 小鼠 单克隆 antibody detecting Neuroligin 1 in IHC 和 ICC. Suitable for 大鼠.
产品编号 ABIN7595501
发货至: 中国

Quick Overview for Neuroligin 1 抗体 (AA 718-843) (FL490) (ABIN7595501)

抗原

See all Neuroligin 1 (NLGN1) 抗体
Neuroligin 1 (NLGN1)

适用

  • 42
  • 40
  • 23
大鼠

宿主

  • 36
  • 29
  • 1
小鼠

克隆类型

  • 40
  • 26
单克隆

标记

  • 22
  • 5
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neuroligin 1 antibody is conjugated to FL490

应用范围

  • 51
  • 26
  • 23
  • 15
  • 14
  • 13
  • 3
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

N97A-31
  • 抗原表位

    • 22
    • 16
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 718-843

    原理

    Anti-Neuroligin-1 Antibody FL490 Conjugate

    特异性

    No off-targets reported for Neuroligin-2, -3, -4 or -4*

    交叉反应

    小鸡, 人, 小鼠, 大鼠

    产品特性

    Description: Our Anti-Neuroligin-1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N97A/31. It is KO validated, detects mouse and rat Neuroligin-1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

    Manufacturer Comment: We produce our Neuroligin-1 mouse monoclonal primary antibody from hybridoma clone N97A/31. It is great in IHC, ICC and is purified by Protein A chromatography.

    纯化方法

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

    纯度

    > 90 % specific antibody

    免疫原

    Fusion protein amino acids 718-843 (intracellular C-terminus) of rat Neuroligin-1 (accession number NP_446320) produced recombinantly in E. Coli

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.09 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    有效期

    12 months
  • 抗原

    Neuroligin 1 (NLGN1)

    别名

    Neuroligin-1

    背景

    Synonyms: Neuroligin-1 (Neuroligin I)

    Target Description: Neuroligin 1 is a member of a large family of alternatively sliced proteins located at the post synaptic surface in the central nervous system, and stains as a post synaptic marker. Neuroligin 1 is involved in cell-cell-interactions by binding to neurexin family members and other postsynaptic proteins to localize receptors and channels in the postsynaptic density. Suggested roles for Neuroligin 1 include synapse function and synaptic signal transmission and maintaining synapse integrity. Mutations in Neuroligans have been implicated in autism and other cognitive disorders.

    Gene Name Alternatives: Nlgn1

    分子量

    120 kDa

    途径

    Synaptic Membrane, Synaptic Vesicle Exocytosis
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