CX3CR1 抗体 (Biotin)
Quick Overview for CX3CR1 抗体 (Biotin) (ABIN7595400)
抗原
See all CX3CR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CX3CR1 Biotin
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特异性
- The rat monoclonal antibody 2A9-1 recognizes an extracellular epitope of CX3CR1, an important regulator of leukocyte trafficking and immune system ballance.
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纯化方法
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
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免疫原
- human CX3CR1 transfectants
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亚型
- IgG2b kappa
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anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 151-250) antibody
CX3CR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 7-20), (Extracellular) antibodyCX3CR1 适用: 小鼠 WB, FACS, IHC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (Extracellular Domain) antibodyCX3CR1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 1-36) antibodyCX3CR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 298-351) antibodyCX3CR1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (N-Term) antibodyCX3CR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 2-21) antibodyCX3CR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (N-Term) antibodyCX3CR1 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 34-47) antibodyVerified CX3CR1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1) (AA 1-355) antibodyCX3CR1 适用: 人 IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 2-8 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
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别名
- CX3CR1
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背景
- CX3CR1 (fractalkine receptor) serves as a regulator of leukocyte trafficking. Its ligand CX3CL1 (fractalkine) can serve bots as chemoatractant (soluble) and as adhesive molecule (membrane bound). Binding to the cell surface expressed ligand leads to rapid induction of firm adhesion of CX3CR1-positive cells without requiring selectin-mediated rolling or activation of integrins. This interaction is important for trafficking of cytotoxic effector lymphocytes regardless of their lineage and mode of target cell recognition, through inflamed endothelium. Similarly, it mediates monocyte/macrophage recruitment to inflamed atherosclerotic plaques, as well as in their homing to non-inflamed tissues, where they can differentiate into dendritic cells. CX3CR1 also promotes cell survival, plays a key role in brain microglia, synapse maturation and regulation of inflammatory response in the central nervous system, it acts as a negative regulator of angiogenesis, and serves as an important regulator of the gut microbiota by controlling immunity to intestinal bacteria and fungi.
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基因ID
- 1524
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UniProt
- P49238
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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