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Integrin alpha 1 抗体 (APC)

This anti-Integrin alpha 1 antibody is a 小鼠 单克隆 antibody detecting Integrin alpha 1 in FACS. Suitable for 人 和 Non-Human Primate.
产品编号 ABIN7595390
发货至: 中国

Quick Overview for Integrin alpha 1 抗体 (APC) (ABIN7595390)

抗原

See all Integrin alpha 1 (ITGA1) 抗体
Integrin alpha 1 (ITGA1)

适用

  • 71
  • 28
  • 14
  • 3
  • 3
人, Non-Human Primate

宿主

  • 62
  • 18
  • 1
  • 1
小鼠

克隆类型

  • 67
  • 15
单克隆

标记

  • 44
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Integrin alpha 1 antibody is conjugated to APC

应用范围

  • 58
  • 26
  • 24
  • 24
  • 21
  • 14
  • 13
  • 13
  • 5
  • 5
  • 3
  • 2
  • 1
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Flow Cytometry (FACS)

克隆位点

TS2-7
  • 原理

    Anti-Hu CD49a APC

    特异性

    The mouse monoclonal antibody TS2/7 recognizes an extracellular epitope of CD49a, the alpha 1 chain of VLA integrin complex, that serves as an adhesion receptor for collagen IV and laminin 1.

    纯化方法

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    human CTL line

    亚型

    IgG1
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    Integrin alpha 1 (ITGA1)

    别名

    CD49a

    背景

    CD49a is the alpha 1 chain of VLA integrin complex (together with CD29, serving as the beta 1 chain), and is expressed on activated T cells, monocytes, NK cells, cultured neuronal cells, melanoma cells, mesenchymal cells (including smooth muscle cells), fibroblasts, hepatocytes, and microvascular endothelium. It binds to collagen IV and laminin 1. It is important for leukocyte migration into tissues. It is upregulated in inflammatory tissues, such as inflammed intestine.

    基因ID

    3672

    UniProt

    P56199

    途径

    EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex
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