Fc epsilon RI/FCER1A 抗体
Quick Overview for Fc epsilon RI/FCER1A 抗体 (ABIN7595383)
抗原
See all Fc epsilon RI/FCER1A (FCER1A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu Fc epsilon RIa Purified
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特异性
- The mouse monoclonal antibody AER-37 [CRA1] recognizes an extracellular epitope of the high-affinity IgE receptor I alpha subunit (Fc epsilon RIa).
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纯化方法
- Purified by protein-A affinity chromatography.
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亚型
- IgG2b kappa
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应用备注
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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别名
- Fc epsilon RIa
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背景
- Folate receptor beta,FOLR2 (folate receptor beta) is a cell surface protein that was originally thought to be specific for placenta, but it can be also expressed in other tissues, including hematopoietic cells. Its expression is increased in malignant tissues. FOLR2 may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. FOLR2 is a marker for macrophages generated in the presence of M-CSF (M2), including M2-like tumor-associated macrophages, which exert potent immunosuppressive functions within the tumor environment, but not GM-CSF (M1), and whose expression correlates with increased folate uptake ability.,Folate receptor beta, FBP, FR-P3, FR-BETA, BETA-HFR, FBP/PL-1
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基因ID
- 2205
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UniProt
- P12319
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途径
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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