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ITGA4 抗体

This anti-ITGA4 antibody is a 小鼠 单克隆 antibody detecting ITGA4 in IHC. Suitable for 人.
产品编号 ABIN7595333
发货至: 中国

Quick Overview for ITGA4 抗体 (ABIN7595333)

抗原

See all ITGA4 抗体
ITGA4 (Integrin alpha 4 (ITGA4))

适用

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宿主

  • 76
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小鼠

克隆类型

  • 99
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单克隆

标记

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This ITGA4 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

OSX14
  • 原理

    Mouse monoclonal to Integrin alpha 4: OSX14 clone

    特异性

    Specific for Integrin α,4

    交叉反应

    交叉反应 (详细)

    Other species not yet tested.

    纯化方法

    IgG

    免疫原

    Integrin alpha 4

    亚型

    IgG
  • 应用备注

    IHC. A dilution of 1 : 500 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    有效期

    12 months
  • 抗原

    ITGA4 (Integrin alpha 4 (ITGA4))

    别名

    Integrin alpha 4

    背景

    FUNCTION: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.

    途径

    Integrin Complex
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