ITGA4 抗体
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北京 101111
Quick Overview for ITGA4 抗体 (ABIN7595333)
抗原
See all ITGA4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse monoclonal to Integrin alpha 4: OSX14 clone
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特异性
- Specific for Integrin α,4
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交叉反应
- 人
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交叉反应 (详细)
- Other species not yet tested.
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纯化方法
- IgG
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免疫原
- Integrin alpha 4
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亚型
- IgG
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应用备注
- IHC. A dilution of 1 : 500 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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有效期
- 12 months
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- ITGA4 (Integrin alpha 4 (ITGA4))
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别名
- Integrin alpha 4
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背景
- FUNCTION: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.
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途径
- Integrin Complex
抗原
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