Tetraspanin 2 抗体 (Extracellular)
Quick Overview for Tetraspanin 2 抗体 (Extracellular) (ABIN7581998)
抗原
See all Tetraspanin 2 (TSPAN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 114-130, Extracellular
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原理
- A Rabbit Polyclonal antibody to Tetraspanin 2 (extracellular)
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序列
- (C)DVAIRHVQSM YEEAYSD
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特异性
- Extracellular, 2nd loop.
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预测反应
- Rat - identical,Human - 14 out of 17 amino acid residues identical
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产品特性
- Anti-Tetraspanin 2 (extracellular) Antibody (ABIN7581998) is a highly specific antibody directed against an extracellular epitope of the mouse protein. The antibody can be used in western blot, immunohistochemistry and flow cytometry applications. It has been designed to recognize TSPAN2 from mouse, rat and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)DVAIRHVQSMYEEAYSD, corresponding to amino acid residues 114 - 130 of mouse TSPAN2
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亚型
- IgG
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anti-Tetraspanin 2 (TSPAN2) (AA 112-187) antibody
TSPAN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Tetraspanin 2 (TSPAN2) (AA 112-187) antibodyTSPAN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A3 unconjugated
anti-Tetraspanin 2 (TSPAN2) (AA 109-137) antibodyTSPAN2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB23467 unconjugated
anti-Tetraspanin 2 (TSPAN2) (AA 112-187) antibodyTSPAN2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tetraspanin 2 (TSPAN2) (AA 108-157) antibodyTSPAN2 适用: 人, 小鼠, Cow, 犬, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 2 (TSPAN2) (AA 116-145), (Middle Region) antibodyTSPAN2 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:200
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Tetraspanin 2 (TSPAN2)
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别名
- TSPAN2
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背景
- Tetraspan NET-3, TSPAN2,Tetraspanin 2 (TSPAN2) is a member of the Tetraspanin family of proteins, that comprises 33 members in humans. The family is characterized by the presence of four transmembrane domains, which give rise to the name "tetraspanin", as well as the presence two extracellular loops (EC1 and EC2), a small cytoplasmic loop, and short N- and C-terminal tails 1,2.Tetraspanins are able to interact with each other and also with numerous partner proteins such as integrins, growth factor receptors and ion channels, to create a dynamic network of interactions known as the tetraspanin-enriched microdomains (TEMs). Consequently, tetraspanins are regarded as molecular organizers and by forming complexes with these proteins, tetraspanins can modulate signal transduction pathways and cellular responses 2,3,4.Although TSPAN2 shares a relatively high homology with well-studied tetraspanins like CD9 (TSPAN29) or CD81 (TSPAN28), it has been less well-characterised up until now 3.Nevertheless, TSPAN2, like the related CD9 and CD81 proteins, has been described in relation to exosome formation, specifically regarding neuroinflammation and microglia activation 5, as well as oligodendrocyte differentiation into myelin-forming glia and in the progression of tumor metastasis by modulating cancer cell motility and invasion 3,5.
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基因ID
- 70747
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UniProt
- Q922J6
抗原
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