Uricase (Uaz) 抗体
This 小鸡 多克隆 antibody specifically detects Uricase in ELISA 和 WB. It exhibits reactivity toward Aspergillus flavus.
产品编号 ABIN7581193
发货至:
中国
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Contact Info
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Quick Overview for Uricase (Uaz) 抗体 (ABIN7581193)
抗原
Uricase (Uaz)
适用
Aspergillus flavus
宿主
小鸡
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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原理
- Aspergillus flavus uricase Antibody
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产品特性
- Chicken Anti-Rasburicase Antibody, Chicken Anti-Aspergillus flavus uricase Antibody
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纯化方法
- Chicken Anti-Aspergillus flavus uricase Antibody has been IgY affinity purified using sepharose resins with immobilized Aspergillus flavus uricase.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Recombinant Aspergillus flavus uricase
Immunogen Type: Recombinant Protein
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应用备注
- Application Note: Affinity purified chicken polyclonal Anti-Aspergillus flavus uricase antibodies have been tested for use in Western Blot and ELISA. This antibody recognizes structured uricase and will work in western blot when the protein are either denatured or in its native form. Although not tested, this antibody being affinity-purified, polyclonal raised using whole A. flavus uricase immunized to chicken could be useful in detection of uricases from Aspergillus spp that share sequence homologies more than 80 % . Specific conditions for reactivity should be optimized by the end user. Western Blot Dilution: User Optimized ELISA Dilution: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.55 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: None -
储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Store vial at 2-8° C. Dilute only prior to immediate use.
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有效期
- 6 months
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- Uricase (Uaz)
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背景
- Aspergillus flavus uricase (Rasburicase) is currently used for the treatment of gout and hyperuricemia occurring in tumor lysis syndrome. Rasburicase, sold under the brand name Elitek in the US and Fasturtec in the EU, is a medication that helps to clear uric acid from the blood. It is a recombinant version of urate oxidase, an enzyme that metabolizes uric acid to allantoin. Urate oxidase is known to be present in many mammals but does not naturally occur in humans. The concentration of uric acid in human serum is 1.5-6.0 mg/dl for women and 2.5-7.0 mg/dl for men. Any increase in the catabolism of purines or decrease in uric acid excretion leads to build up of uric acid in the form of monosodium urate crystals in joints or soft tissues. Moreover, hyperuricemia is also observed tumor lysis syndrome (TLS) and is caused by massive tumor cell lysis followed by catabolism of the nucleic acids to uric acid after chemotherapeutic treatment.
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UniProt
- Q00511
抗原
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