PIKFYVE 抗体
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北京 101111
Quick Overview for PIKFYVE 抗体 (ABIN7581220)
抗原
See all PIKFYVE 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit polyclonal antibody to murine PIKfyve with reactivity to mouse/rat and human PIKfyve
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特异性
- The PIKfyve antibody is directed at an N-terminal region of PIKfyve and detects mammalian forms of PIKfyve with an expected molecular weight of approximately 237 kDa.
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纯化方法
- affinity purified using Protein A chromatography
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免疫原
- synthetic fusion peptide of aa 1-100
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亚型
- IgG
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应用备注
- IF/ICC – 2-5 ug/mL Western – 1.0 ug/mL Immunoprecipitation – 1.0 ug/mL Other in vitro and cellular applications are possible using this antibody, but have not been verified.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- protect from direct light and store at 4°C for up to 30 days. For long term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles.
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- PIKFYVE (phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))
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别名
- PIKfyve
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背景
- PIKfyve (aka PIP5K3) is an approximately 237 kDa lipid kinase enzyme. It is primarily found on early endosomes where it synthesizes PI(3,5)P2 from membrane-associated PI(3)P. Endosomal PIKfyve forms a complex with ArPIKfyve (Vac14) and Sac3 to regulate fusion, transport, and export of endosomes in the cell. PIKfyve also has protein kinase activity in the form of self-regulatory autophosphorylation.
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途径
- Inositol Metabolic Process
抗原
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