DGKZ 抗体
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北京 101111
Quick Overview for DGKZ 抗体 (ABIN7581194)
抗原
See all DGKZ 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit polyclonal antibody against human diacylglycerol kinase zeta (DGKζ)
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交叉反应 (详细)
- Shown to recognize a ~117kDa protein in wild-type DGK ζ protein with no cross activity to recombinant DGKα Protein.
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纯化方法
- Serum
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免疫原
- peptide = LENRQHYQMIQREDQE
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亚型
- IgG
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应用备注
- WB – 1:1000 Other in vitro and cellular applications are possible using this antibody, but have not been verified.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01% thiomersal
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4 °C for up to 30 days. Aliquot and store at -20 °C if longer storage is necessary. Antibody is stable for at least 2 years when stored at -20 °C. Avoid repeated freeze/thaw cycles.
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- DGKZ (Diacylglycerol Kinase, zeta (DGKZ))
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别名
- DGK Zeta
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背景
- DGK catalyzes a reaction terminating the protein kinase C (PKC)mediated signaling by converting diacylglycerol (DAG) to phosphatidic acid (PA), a signaling lipid which is involved in DNA synthesis, phospholipid synthesis, and regulation of several enzymes. DAG is an intermediate in phospholipid synthesis which functions as an allosteric activator of PKC. Research shows the zeta isoform of DGK undergoes tissue-specific alternative splicing resulting in an elongated N terminus enzyme predominantly in muscle.
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途径
- Myometrial Relaxation and Contraction
抗原
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