OPRL1 抗体 (AA 1-47) (Cy3)
Quick Overview for OPRL1 抗体 (AA 1-47) (Cy3) (ABIN725963)
抗原
See all OPRL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-47
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Horse,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse Nociceptin receptor
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- OPRL1 (Opiate Receptor-Like 1 (OPRL1))
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别名
- Nociceptin receptor
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背景
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Synonyms: KOR3, ORGC, ORL1, Oprl, XOR1, morc, KOR-3, LC132, MOR-C, Nociceptin receptor, K3 opiate receptor, Kappa-type 3 opioid receptor, Orphanin FQ receptor, Oprl1, Oor
Background: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
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基因ID
- 18389
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UniProt
- P35377
抗原
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