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DLG4 抗体 (AA 468-560)

This anti-DLG4 antibody is a 兔 多克隆 antibody detecting DLG4 in WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 大鼠, 人, 小鼠 和 猴. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN725930
发货至: 中国

Quick Overview for DLG4 抗体 (AA 468-560) (ABIN725930)

抗原

See all DLG4 抗体
DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

适用

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大鼠, 人, 小鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This DLG4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 16
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    AA 468-560

    交叉反应

    人, 猴, 小鼠, 大鼠

    预测反应

    Dog,Cow,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PSD95

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Ku, Li, Gao, Zhang, Yan, Ji, Li, Sang: "NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration." in: Particle and fibre toxicology, Vol. 14, Issue 1, pp. 34, (2018) (PubMed).

    Luo, Guo, Fan, Lu, Chen, Wang, Shao, Wu, Xu, Lü: "Niche astrocytes promote the survival, proliferation and neuronal differentiation of co-transplanted neural stem cells following ischemic stroke in rats." in: Experimental and therapeutic medicine, Vol. 13, Issue 2, pp. 645-650, (2017) (PubMed).

    Li, Wei, Bai, Li, Huang, Lin, Hou, Deng, Zhou, Zhang, Chen: "MicroRNA-574 is involved in cognitive impairment in 5-month-old APP/PS1 mice through regulation of neuritin." in: Brain research, Vol. 1627, pp. 177-88, (2015) (PubMed).

    Zhao, Li, Wei, Savage, Zhou, Ma: "Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring." in: Neurobiology of disease, Vol. 68, pp. 145-55, (2014) (PubMed).

    Wang, Niu, Zhu, Han, Luo, Zhou, Wang: "Changes in memory and synaptic plasticity induced in male rats after maternal exposure to bisphenol A." in: Toxicology, Vol. 322, pp. 51-60, (2014) (PubMed).

    Zhang, Zheng, Wan, Shao, Liu, Zhang, Zhang: "The potential use of H102 peptide-loaded dual-functional nanoparticles in the treatment of Alzheimer's disease." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 192, pp. 317-24, (2014) (PubMed).

  • 抗原

    DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

    别名

    PSD95

    背景

    Synonyms: PSD95, SAP9, SAP-9, Disks large homolog 4, Postsynaptic density protein 95, PSD-95, Synapse-associated protein 9, DLG4

    Background: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

    基因ID

    1742

    UniProt

    P78352

    途径

    Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
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