IRS2 抗体 (AA 501-600)
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北京 101111
Quick Overview for IRS2 抗体 (AA 501-600) (ABIN725840)
抗原
See all IRS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-600
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human IRS-2
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亚型
- IgG
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anti-Insulin Receptor Substrate 2 (IRS2) (AA 510-650) antibody
IRS2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (AA 766-1001) antibodyIRS2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (AA 1309-1338), (C-Term) antibodyIRS2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15641 unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (C-Term) antibodyIRS2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (AA 985-1255) antibodyIRS2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) antibodyIRS2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (AA 1288-1338) antibodyIRS2 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor Substrate 2 (IRS2) (C-Term) antibodyIRS2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8164-8170, (2017) (PubMed).
: "Donor Graft MicroRNAs: A Newly Identified Player in the Development of New-onset Diabetes After Liver Transplantation." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Vol. 17, Issue 1, pp. 255-264, (2016) (PubMed).
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: "Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8164-8170, (2017) (PubMed).
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- IRS2 (Insulin Receptor Substrate 2 (IRS2))
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别名
- IRS-2
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背景
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Synonyms: IRS-2, Insulin receptor substrate 2, IRS2
Background: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions, however, the distinct physiological roles of each IRS are unclear. Summary: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
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基因ID
- 8660
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UniProt
- Q9Y4H2
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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