CD16 抗体 (Elab Fluor®700)
Quick Overview for CD16 抗体 (Elab Fluor®700) (ABIN7566955)
抗原
See all CD16 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Elab Fluor®700 Anti-Human CD16 Antibody[3G8]
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亚型
- IgG1, kappa
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应用备注
- Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
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说明
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Matching Isotype Control: E-AB-F09792M1
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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有效期
- 12 months
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- CD16
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别名
- CD16
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背景
- Fc gamma receptor,Fc gamma receptor 3,FcγRIII,CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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基因ID
- 941
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UniProt
- P08637, O75015
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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