CD47 抗体 (Elab Fluor®700)
Quick Overview for CD47 抗体 (Elab Fluor®700) (ABIN7566750)
抗原
See all CD47 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Elab Fluor®700 Anti-Human CD47 Antibody[CC2C6D4]
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亚型
- IgG1, kappa
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应用备注
- Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
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说明
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Matching Isotype Control: E-AB-F09792M1
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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有效期
- 12 months
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- CD47
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别名
- CD47
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背景
- Cd47,IAP,Integrin-associated protein,Leukocyte surface antigen CD47,CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47, in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
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基因ID
- 961
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UniProt
- Q08722
抗原
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