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CD22 抗体 (Elab Fluor®700)

This anti-CD22 antibody is a 小鼠 单克隆 antibody detecting CD22 in FACS. Suitable for 小鼠.
产品编号 ABIN7566715
发货至: 中国

Quick Overview for CD22 抗体 (Elab Fluor®700) (ABIN7566715)

抗原

See all CD22 抗体
CD22 (CD22 Molecule (CD22))

适用

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小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD22 antibody is conjugated to Elab Fluor®700

应用范围

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Flow Cytometry (FACS)

克隆位点

Cy34-1
  • 原理

    Elab Fluor®700 Anti-Mouse CD22 Antibody[Cy34.1]

    亚型

    IgG1, kappa
  • 应用备注

    Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

    说明

    Matching Isotype Control: E-AB-F09793M1

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

    储存条件

    4 °C

    储存方法

    This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

    有效期

    12 months
  • 抗原

    CD22 (CD22 Molecule (CD22))

    别名

    CD22

    背景

    Siglec2,B-cell receptor CD22,B-lymphocyte cell adhesion molecule,BL-CAM,CD22,Cd22,Lyb-8,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig μ chain are augmented in the presence of Cy34.1 mAb.

    基因ID

    12483

    UniProt

    P35329
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