CD86 抗体 (Elab Fluor®Violet 610)
Quick Overview for CD86 抗体 (Elab Fluor®Violet 610) (ABIN7566683)
抗原
See all CD86 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Elab Fluor®Violet 610 Anti-Mouse CD86 Antibody[GL-1]
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亚型
- IgG2a, kappa
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应用备注
- Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
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说明
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Matching Isotype Control: E-AB-F09832T
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限制
- 仅限研究用
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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有效期
- 12 months
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- CD86
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别名
- CD86
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背景
- Activation B7-2 antigen,Cd86,ETC-1,Early T-cell costimulatory molecule 1,T-lymphocyte activation antigen CD86,CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
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基因ID
- 12524
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UniProt
- P42082
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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