2B4 抗体 (PE,Cy5)
Quick Overview for 2B4 抗体 (PE,Cy5) (ABIN7566586)
抗原
See all 2B4 (CD244) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PE/Cyanine5 Anti-Human CD244 Antibody[C1.7]
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亚型
- IgG1, kappa
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应用备注
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Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test -
说明
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Matching Isotype Control: abo_E-AB-F09792G
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
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储存条件
- 4 °C
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储存方法
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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有效期
- 12 months
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- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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别名
- CD244
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背景
- 2B4,SLAMF4,CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
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基因ID
- 51744
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UniProt
- Q9BZW8
抗原
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