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Recombinant SARS-CoV-2 Nucleocapsid 抗体

This anti-SARS-CoV-2 Nucleocapsid antibody is a Human 单克隆 antibody detecting SARS-CoV-2 Nucleocapsid in ELISA. Suitable for SARS Coronavirus-2 (SARS-CoV-2).
产品编号 ABIN7566446
发货至: 中国

Quick Overview for Recombinant SARS-CoV-2 Nucleocapsid 抗体 (ABIN7566446)

抗原

See all SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) 抗体
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

抗体类型

Recombinant Antibody

适用

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SARS Coronavirus-2 (SARS-CoV-2)

宿主

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Human

克隆类型

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单克隆

标记

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This SARS-CoV-2 Nucleocapsid antibody is un-conjugated

应用范围

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ELISA

克隆位点

Capsi-1
  • 原理

    anti-SARS-CoV-2 N Protein, mAb (rec.) (Capsi-1) (preservative free)

    产品特性

    Recombinant Antibody. Recognizes and binds to recombinant SARS-CoV-2 N protein. Application: ELISA. Liquid, in PBS ( pH 7.4). Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many other wild animals. Recently, a new severe acute respiratory syndrome beta-coronavirus called SARS-CoV-2 (or 2019-nCoV) has emerged, which causes an epidemic of acute respiratory syndrome (called coronavirus human disease 2019 or COVID-19). SARS-CoV-2 shares 79.5 % sequence identity with SARS-CoV and is 96.2 % identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. SARS-CoV-2 contains 4 structural proteins, including Envelope (E), Membrane (M), Nucleocapsid (N) and Spike (S), which is a transmembrane protein, composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells, causing mainly infection of human respiratory cells. The N protein contains two domains, both of them bind the virus RNA genome via different mechanisms.

    Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many other wild animals. Recently, a new severe acute respiratory syndrome beta-coronavirus called SARS-CoV-2 (or 2019-nCoV) has emerged, which causes an epidemic of acute respiratory syndrome (called coronavirus human disease 2019 or COVID-19). SARS-CoV-2 shares 79.5 % sequence identity with SARS-CoV and is 96.2 % identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. SARS-CoV-2 contains 4 structural proteins, including Envelope (E), Membrane (M), Nucleocapsid (N) and Spike (S), which is a transmembrane protein, composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells, causing mainly infection of human respiratory cells. The N protein contains two domains, both of them bind the virus RNA genome via different mechanisms.

    纯化方法

    Puified

    纯度

    >95 % (SDS-PAGE)

    内毒素水平

    <1EU/mg (LAL method)

    免疫原

    Recombinant SARS-CoV-2 nucleocapsid protein.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid, in PBS ( pH 7.4).

    储存液

    Without preservative

    注意事项

    Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    +4°C

    Stable for at least 1 year after receipt when stored at -20°C.

  • 抗原

    SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

    别名

    SARS-CoV-2 N Protein

    物质类

    Viral Protein
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