Resistin 抗体
Quick Overview for Resistin 抗体 (ABIN7566444)
抗原
See all Resistin (RETN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-Resistin (human), mAb (HRES106)
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产品特性
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Monoclonal antibody. Recognizes human resistin. Does not cross-react with mouse resistin. Applications: ELISA. Isotype: Mouse IgG2akappa. Clone: HRES106. Liquid. In PBS containing 0.02 % sodium azide. The adipokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMα/FIZZ 1 and RELMβ/FIZZ 2) of FIZZ (found in inflammatory zone) that are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM. Resistin is secreted by obese subcutaneous adipose tissue and impaired myotube thickness and nuclear fusion by activation of the classical NF-κB pathway. In human, resistin levels are increased in the serum of obese individuals and resistin is used as a severity marker of asthma.
The adipokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) that are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM. Resistin is secreted by obese subcutaneous adipose tissue and impaired myotube thickness and nuclear fusion by activation of the classical NF-kappaB pathway. In human, resistin levels are increased in the serum of obese individuals and resistin is used as a severity marker of asthma.
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纯化方法
- Puified
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Recombinant human resistin.
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亚型
- IgG2a kappa
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anti-Resistin (RETN) (AA 21-114) antibody
RETN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Resistin (RETN) antibodyRETN 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) antibodyRETN 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) (AA 21-114) antibodyRETN 适用: 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) (AA 17-108) antibodyRETN 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Resistin (RETN) (AA 45-114) antibodyRETN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) (AA 19-109) antibodyRETN 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) antibodyRETN 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Resistin (RETN) (AA 1-108) antibodyRETN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Resistin (RETN) antibodyRETN 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- In PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
Stable for at least 1 year after receipt when stored at -20°C.
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- Resistin (RETN)
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别名
- Resistin
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UniProt
- Q9HD89
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途径
- Feeding Behaviour, Smooth Muscle Cell Migration
抗原
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