CLIC1 抗体
Quick Overview for CLIC1 抗体 (ABIN7565990)
抗原
See all CLIC1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CLIC1 Antibody
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交叉反应 （详细）
- This antibody is specific for human CLIC1.
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产品特性
- Synonyms: Rabbit Anti-CLIC1 Antibody, Chloride Intracellular Channel 1, Regulatory Nuclear Chloride Ion Channel Protein, Chloride Intracellular Channel Protein 1, Nuclear Chloride Ion Channel 27, Chloride Channel ABP, NCC27, HRNCC, G6, Nuclear Chloride Ion Channel Protein, RNCC Protein, P64CLCP
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纯化方法
- This product was Protein A purified from monospecific antiserum by chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with human CLIC1 recombinant protein.
Immunogen Type: Recombinant Protein
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anti-Chloride Intracellular Channel 1 (CLIC1) (AA 1-241) antibody
CLIC1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 42-241) antibodyCLIC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (N-Term) antibodyCLIC1 适用: 人, 大鼠, 小鼠, Cow, 山羊, 马, 豚鼠, 兔, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 1-241) antibodyCLIC1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 79-241) antibodyCLIC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 42-241) antibodyCLIC1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) antibodyCLIC1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 1-242) antibodyCLIC1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) (AA 1-242) antibodyCLIC1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Chloride Intracellular Channel 1 (CLIC1) antibodyCLIC1 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Application Note: Anti-CLIC1 has been tested in ELISA, Western Blot, and Immunoprecipitation. Expect a band at ~27kda in western blot using appropriate tissues and lysates. Positive controls used in western blot include CLIC1 overexpressing HEK293, WM-115, and HL-60 whole cell lysates. Western Blot Dilution: 1 μg/mL Immunoprecipitation Dilution: User Optimized ELISA Dilution: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.06 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
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有效期
- 12 months
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- CLIC1 (Chloride Intracellular Channel 1 (CLIC1))
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别名
- CLIC1
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背景
- Background: CLIC1 (Chloride Intracellular Channel 1) can insert into membranes and form chloride ion channels. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family, the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. This channel activity depends on the pH . Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. Anti-CLIC1 is useful for researchers interested in Blackwater Fever and Penicilliosis diseases, along with Cancer, Neuroscience, and activation of cAMP-Dependent PKA.
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基因ID
- 1192
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NCBI登录号
- NP_001274522
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UniProt
- O00299
抗原
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