CGA 抗体
Quick Overview for CGA 抗体 (ABIN7565946)
抗原
See all CGA 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- hCG Alpha chain Antibody
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交叉反应 (详细)
- This affinity purified antibody is directed against hCG alpha.
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产品特性
- Synonyms: Goat Anti-Human Chorionic Gonadotropin Alpha Antibody, Goat anti-hCGa Antibody, α-hCG, a-hCG, alpha-hCG, Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, CG-alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain
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纯化方法
- This affinity purified antibody is directed against hCG alpha.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Anti-Human Chorionic Gonadotropin Alpha Antibody was prepared from whole goat serum produced by repeated immunizations with Hu Chorionic Gonadotropin Alpha Subunit protein.
Immunogen Type: Native Protein
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应用备注
- Application Note: Anti-Human Chorionic Gonadotropin (hCG) Alpha Antibody has been tested in ELISA and WB. Expect a band at ~14.9 kDa for the alpha chain in western blot using appropriate tissues and lysates. ELISA reactivity expected against alpha hCG with an expected titer of ~1:100,000 and full hCG at ~1:50,000 dilution. Western Blot Dilution: 1:1000 ELISA Dilution: 1:20,000-1:100,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.78 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))
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别名
- CGA
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背景
- Background: Human Chorionic Gonadotropin (hCG) is a member of the glycoprotein hormone family which includes lutropin, follitropin, and thyrotropin. These hormones are heterodimers consisting of a common alpha subunit, and a unique beta chain which confers their biological specificity to the hormones. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. HCG is secreted in large quantities by normal trophoblasts. Its presence is in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. CGA is extracellular and secreted, expressed in over 90 organs, but has its highest expression level in placenta. Anti-hCG alpha detects hCG alpha in human cells and tissue and could be useful in detecting cells and tumors of trophoblastic origin such as choriocarcinoma. Anti-hCG Antibody is useful for researchers interested in pregnancy, hormone research, and cancer research.
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基因ID
- 1081
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NCBI登录号
- NP_000726
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UniProt
- P01215
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途径
- Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport, Peptide Hormone Metabolism
抗原
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