CGRP 抗体
Quick Overview for CGRP 抗体 (ABIN7565820)
抗原
See all CGRP (CALCA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Procalcitonin (9D9.E11.C3.E8.F4.D4) Antibody
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交叉反应 (详细)
- This antibody is specific for human Procalcitonin.
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产品特性
- Synonyms: mouse anti-procalcitonin antibody, calcitonin isoform CT preproprotein, calcitonin-related polypeptide alpha, CT, KC, CGRP, CALC1, CGRP1, CGRP-I
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纯化方法
- Anti-Procalcitonin Antibody was purified from concentrated tissue culture supernate by Protein A chromatography.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Procalcitonin Antibody was produced in mice prepared by repeated immunizations with full-length recombinant human Procalcitonin protein.
Immunogen Type: Recombinant Protein
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亚型
- IgG1 lambda
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应用备注
- Application Note: Anti-Procalcitonin [9D9.E11] antibody was tested by ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Western Blot Dilution: 1:1,000 - 1:2,000 ELISA Dilution: User Optimized Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))
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别名
- CALCA
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背景
- Background: Anti-Procalcitonin antibody detects human Procalcitonin. Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, a N terminal residue, calcitonin and katacalcin. Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock. This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P06881
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途径
- Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour
抗原
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