Hemoglobin Subunit beta 抗体 (N-Term)
Quick Overview for Hemoglobin Subunit beta 抗体 (N-Term) (ABIN7565774)
抗原
See all Hemoglobin Subunit beta (HBB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Hemoglobin A (beta chain) Antibody
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交叉反应 （详细）
- This protein A purified mouse monoclonal antibody reacts specifically with human HbA beta chain isoform.
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产品特性
- Synonyms: mouse anti-HbA antibody, mouse anti-hemoglobin antibody, Hemoglobin beta subunit, Hemoglobin subunit beta, Hemoglobin beta chain, HBB, HBA, Hbβ Antibody, LVV-hemorphin-7, Spinorphin, Sickle Cell Disease (SCD)
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纯化方法
- Anti-Hemoglobin beta β is purified from tissue culture supernatant by protein A purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: Anti-Hemoglobin A (beta chain) Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb beta-subunit conjugated to KLH.
Immunogen Type: Conjugated Peptide
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亚型
- IgG2a lambda
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anti-Hemoglobin beta (HBB) (AA 1-147) antibody
HBB 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hemoglobin beta (HBB) (AA 1-145) antibodyHBB 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemoglobin beta (HBB) (AA 38-147) antibodyHBB 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 7B12 unconjugated
anti-Hemoglobin beta (HBB) (AA 1-147) antibodyHBB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hemoglobin beta (HBB) (AA 1-147) antibodyHBB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hemoglobin beta (HBB) (AA 38-147) antibodyHBB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H3 unconjugated
anti-Hemoglobin beta (HBB) (AA 80-107), (C-Term) antibodyHBB 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18724 unconjugated
anti-Hemoglobin beta (HBB) (AA 38-147) antibodyHBB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hemoglobin beta (HBB) (AA 38-148) antibodyHBB 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 7B12 unconjugated
anti-Hemoglobin beta (HBB) (N-Term) antibodyHBB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 14G2-G11-F11 unconjugated
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应用备注
- Application Note: Anti-Hemoglobin A (beta chain) (MOUSE) antibody has been tested by ELISA and western blot. This antibody is designed for use in lateral flow. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 16 kDa. Western Blot Dilution: 1 μg/mL ELISA Dilution: 1:20,000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.00 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
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有效期
- 12 months
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- Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))
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别名
- HBB
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背景
- Background: HbA antibodies detect the hemoglobin beta subunit wild type variant A isoform. Functional adult hemoglobin (Hb) is a hetero tetramer composed of 2 alpha and 2 beta subunits (α2β2). Common isoform variants of hemoglobin include HbA, HbS, HbC, HbF, and HbA-2. Sickle cell disease (SCD), thalassemias and hemoglobinopathies occur when aberrant forms of hemoglobin are expressed in children and adults. Globin gene mutations affect the structure and expression levels of Hb. Sickle cell disease and the more benign sickle cell trait are observed in more than 100 million people globally. Perhaps the most significant mutation is the E6V in the beta subunit and the cause of SCD, but other relevant isoforms of Hb are observed. HbA antibody cross reacts with HbA-2 but does not react other forms Hb. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.
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基因ID
- 3043
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NCBI登录号
- NP_000509
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UniProt
- P68871
抗原
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