PP2A alpha/beta 抗体 (AA 205-309)
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北京 101111
Quick Overview for PP2A alpha/beta 抗体 (AA 205-309) (ABIN723875)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 205-309
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Cow,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PP-2A
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亚型
- IgG
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anti-PP2A alpha/beta (PP2A A/B) (pTyr307) antibody
PP2A A/B 适用: 人, 大鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-PP2A alpha/beta (PP2A A/B) antibodyPP2A A/B 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2300 unconjugated Recombinant Antibody
anti-PP2A alpha/beta (PP2A A/B) antibodyPP2A A/B 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Feasibility of ?-Sheet Breaker Peptide-H102 Treatment for Alzheimer's Disease Based on ?-Amyloid Hypothesis." in: PLoS ONE, Vol. 9, Issue 11, pp. e112052, (2014) (PubMed).
: "Involvement of GSK3 and PP2A in ginsenoside Rb1's attenuation of aluminum-induced tau hyperphosphorylation." in: Behavioural brain research, Vol. 241, pp. 228-34, (2013) (PubMed).
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: "Feasibility of ?-Sheet Breaker Peptide-H102 Treatment for Alzheimer's Disease Based on ?-Amyloid Hypothesis." in: PLoS ONE, Vol. 9, Issue 11, pp. e112052, (2014) (PubMed).
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- PP2A alpha/beta (PP2A A/B)
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别名
- PP2A alpha / beta
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背景
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Synonyms: RP-C, PP2Ac, PP2CA, PP2Calpha, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, PPP2CA
Background: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
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基因ID
- 5515
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UniProt
- P67775
抗原
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