Metronidazole 抗体 (Biotin)
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- 抗原
- Metronidazole
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适用
- 化学剂
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- Biotin
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Purified by Protein G.
- 免疫原
- KLH conjugated with Metronidazole
- 克隆位点
- 1C2
- 亚型
- IgG
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anti-Metronidazole antibody
适用: 化学剂 IHC (p), IF (p) 宿主: 小鼠 Monoclonal 1C2 unconjugated
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- 应用备注
- IHC-P 1:100-500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 4°C
- 有效期
- 12 months
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- 抗原
- Metronidazole
- 物质类
- Chemical
- 背景
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Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal.Metronidazole, taken up by diffusion, is selectively absorbed by anaerobic bacteria and sensitive protozoa. Once taken up by anaerobes, it is non-enzymatically reduced by reacting with reduced ferredoxin, which is generated by pyruvate oxido-reductase. Many of the reduced nitroso intermediates will form sulfinamides and thioether linkages with cysteine-bearing enzymes, thereby deactivating these critical enzymes. As many as 150 separate enzymes are affected.In addition or alternatively, the metronidazole metabolites are taken up into bacterial DNA, and form unstable molecules. This function only occurs when metronidazole is partially reduced, and because this reduction usually happens only in anaerobic cells, it has relatively little effect upon human cells or aerobic bacteria.
Synonyms: 2-Methyl-5-nitroimidazole-1-ethanol
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