Recombinant NCR1 抗体
Quick Overview for Recombinant NCR1 抗体 (ABIN7543464)
抗原
See all NCR1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Nkp46 [29A1.4], Rabbit IgG, kappa
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特异性
- This antibody is specific for mouse NKp46-Fc.
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing rats with mouse NKp46-Fc recombinant protein.
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亚型
- IgG kappa
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应用备注
- The original format of this antibody was used in an FC analysis to detect NKp46 expression on NK cells and to activate NK in an NK cell stimulation assay (Walzer et al., 2007, PMID: 17360655). This antibody was used as a component of bispecific NKCEs (Natural Killer Cell Engagers) to redirect the cytotoxic activity of NK cells towards human CD20-expressing tumor cells in a transplantable xenogeneic in vivo solid tumor model (Gauthier et al., 2019, PMID: 31155232).
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
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别名
- Nkp46
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背景
- CD335, NK-p46, NKp46, mNKp46, mAR-1, Activating receptor 1, Lymphocyte antigen 94, Natural killer cell p46-related protein, Natural cytotoxicity triggering receptor 1
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UniProt
- Q8C567
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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