Recombinant Ferritin 抗体
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Quick Overview for Recombinant Ferritin 抗体 (ABIN7543451)
抗原
See all Ferritin (FE) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Ferritin [AMB8LK], Rabbit IgG, kappa
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特异性
- This antibody binds human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing female Balb/c mice with ferritin extracted from human spleen cells.
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亚型
- IgG kappa
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anti-Ferritin (FE) antibody
FE 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ferritin (FE) antibodyKD Validated FE 适用: 人, 小鼠, 大鼠 WB, ICC, IF 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
- This antibody was capable of immunoprecipitating ferritin (PMID: 6817879). The original antibody binds human ferritin with a binding affinity of Kd= 5.1nM (EP2193147). The thiolated version of this antibody was conjugated to maleimide-activated polylactide nanoparticles (NPs) to generate immunonanoparticles, which may carry drugs to desired overexpressing antigen cells potentially leading to improved drug therapy and reduced systemic adverse effects (PMID: 19835957). Preclinical studies showed that the immunoconjugate with 90Y has 98 % stability over 7 days. A very good pancreatic adenocarcinoma tumor targeting was observed especially with the Bz-DTPA-AMB8LK (PMID: 17383579)
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Ferritin (FE)
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别名
- Ferritin
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背景
- FTMT, FTL, FTH1, Ferritin mitochondrial, B8
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UniProt
- Q8N4E7
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途径
- Transition Metal Ion Homeostasis
抗原
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