Recombinant Ferritin 抗体
FE
适用: 人
IP
宿主: 兔
Monoclonal
AMB8LK
unconjugated
Recombinant Antibody
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- 抗原 See all Ferritin (FE) 抗体
- Ferritin (FE)
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This Ferritin antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP)
- 原理
- Anti-Ferritin [AMB8LK], Rabbit IgG, kappa
- 特异性
- This antibody binds human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis.
- 产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
- 纯化方法
- Protein A affinity purified
- 免疫原
- The original antibody was generated by immunizing female Balb/c mice with ferritin extracted from human spleen cells.
- 克隆位点
- AMB8LK
- 亚型
- IgG kappa
- Top Product
- Discover our top product FE Primary Antibody
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anti-Ferritin (FE) antibody
FE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This antibody was capable of immunoprecipitating ferritin (PMID: 6817879). The original antibody binds human ferritin with a binding affinity of Kd= 5.1nM (EP2193147). The thiolated version of this antibody was conjugated to maleimide-activated polylactide nanoparticles (NPs) to generate immunonanoparticles, which may carry drugs to desired overexpressing antigen cells potentially leading to improved drug therapy and reduced systemic adverse effects (PMID: 19835957). Preclinical studies showed that the immunoconjugate with 90Y has 98 % stability over 7 days. A very good pancreatic adenocarcinoma tumor targeting was observed especially with the Bz-DTPA-AMB8LK (PMID: 17383579)
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- 抗原
- Ferritin (FE)
- 别名
- Ferritin (FE 产品)
- 背景
- FTMT, FTL, FTH1, Ferritin mitochondrial, B8
- UniProt
- Q8N4E7
- 途径
- Transition Metal Ion Homeostasis
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