Recombinant HbA1c 抗体 (N-Term)
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Quick Overview for Recombinant HbA1c 抗体 (N-Term) (ABIN7543441)
抗原
See all HbA1c 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Anti-HbA1c [1G8], Rabbit IgG, kappa
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特异性
- This antibody binds human hemoglobin glycated at the N-terminal valine of the hemoglobin β chain and does not cross react with non-glycated hemoglobin. Glycated hemoglobin is formed by the conjugation of a hexose sugar to the beta-chain of hemoglobin. Glycosylated hemoglobin A1c (HbA1c) levels are used as an indicator of average plasma glucose concentration in diabetic patients. Levels of more than 48 mmol/mol (6.5 % ) are used as a criterion for the diagnosis of diabetes. Higher levels of HbA1c are also associated with cardiovascular disease.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing BALB/c mice with synthetic N-terminal glycopeptide (VHLTPEC) and KLH conjugate.
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亚型
- IgG kappa
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anti-Glycated Hemoglobin HbA1c (HbA1c) antibody
HbA1c 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycated Hemoglobin HbA1c (HbA1c) antibodyHbA1c 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
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应用备注
- This antibody is recommended for detection of HbA1c levels in plasma and blood samples. The binding reactivity of this antibody towards HbA1c and non-glycated hemoglobin was done using indirect ELISA. The binding reactivity of this antibody to HbA1c was compared to commercially available anti-HbA1c antibody BM300-F7C2 and it was reported that this antibody showed better specificity for HbA1c (CN110724671).
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说明
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This is a chimeric antibody made using the variable domain sequences of the original Mouse IgG2a to improve compatibility with existing reagents, assays, and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- HbA1c (Glycated Hemoglobin HbA1c (HbA1c))
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别名
- HbA1c
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背景
- GHb, A1C, HBB, hemoglobin A1c, glycosylated hemoglobin HbA1c, glycosylated hemoglobin, glycohemoglobin, glycated hemoglobin, haemoglobin, haemoglobin A1c, Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain
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UniProt
- P68871
抗原
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