Recombinant Progesterone Receptor 抗体
Quick Overview for Recombinant Progesterone Receptor 抗体 (ABIN7543416)
抗原
See all Progesterone Receptor (PGR) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Progesterone Receptor [14B3], Rabbit IgG, kappa
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特异性
- The antibody is specific for PR protein. PR is a protein molecule, a cellular core receptor belonging to a steroidal superfamily, which can be bonded to the corresponding hormone to form a hormone-receptor complex, enabling hormones to exert their biological effects.
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产品特性
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Original Species of Ab: Rabbit
Original Format of Ab: IgG
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing rabbits with PR protein.
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亚型
- IgG kappa
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应用备注
- The specificity of the original format of the antibody was confirmed by ELISA analysis (affinity constant of 1.82 x 10^10 M-1). The antibody specifically detected PR protein in Western blot analysis. The antibody 14B3 and the commercial antibody 1E2 were used to stain breast cancer and endometrial. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 14B3 was higher than the commercial antibody (CN113583132A).
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Progesterone Receptor (PGR)
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别名
- Progesterone Receptor
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背景
- PR, Nuclear receptor subfamily 3 group C member 3
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UniProt
- P06401
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
抗原
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