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Recombinant Progesterone Receptor 抗体

This 小鼠 Chimeric antibody specifically detects Progesterone Receptor in WB, IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7543415
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant Progesterone Receptor 抗体 (ABIN7543415)

抗原

See all Progesterone Receptor (PGR) 抗体
Progesterone Receptor (PGR)

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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Chimeric

标记

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This Progesterone Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

14B3
  • 原理

    Anti-Progesterone Receptor [14B3], Mouse IgG1, kappa

    特异性

    The antibody is specific for PR protein. PR is a protein molecule, a cellular core receptor belonging to a steroidal superfamily, which can be bonded to the corresponding hormone to form a hormone-receptor complex, enabling hormones to exert their biological effects.

    产品特性

    Original Species of Ab: Rabbit

    Original Format of Ab: IgG

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by immunizing rabbits with PR protein.

    亚型

    IgG1 kappa
  • 应用备注

    The specificity of the original format of the antibody was confirmed by ELISA analysis (affinity constant of 1.82 x 10^10 M-1). The antibody specifically detected PR protein in Western blot analysis. The antibody 14B3 and the commercial antibody 1E2 were used to stain breast cancer and endometrial. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 14B3 was higher than the commercial antibody (CN113583132A).

    说明

    This chimeric mouse antibody was made using the variable domain sequences of the original Rabbit IgG format for improved compatibility with existing reagents assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    Progesterone Receptor (PGR)

    别名

    Progesterone Receptor

    背景

    PR, Nuclear receptor subfamily 3 group C member 3

    UniProt

    P06401

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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