Recombinant MUC16 抗体
Quick Overview for Recombinant MUC16 抗体 (ABIN7543399)
抗原
See all MUC16 (CA125) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CA125 [20E3], Rabbit IgG, kappa
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特异性
- The original antibody is specific for CA125. CA125 is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. This antigen that is the basis for a widely used serum assay for the monitoring of patients with ovarian epithelial cancer.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2b
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing mice with recombinant protein CA125.
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亚型
- IgG kappa
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应用备注
- The antibody 20E3 and the commercial antibody TA347 were used to stain ovarian slurry adenocarcinoma and ovarian mucous adenocarcinoma in immunohistochemistry. Results showed the antibody specificity is comparable to the commercial antibody. Further, the staining intensity of the antibody 20E3 was higher than the commercial antibody (CN113061186A).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
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别名
- CA125
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背景
- TA347, Mucin-16, MUC-16, Ovarian cancer-related tumor marker CA125, CA-125, Ovarian carcinoma antigen CA125, CGMCC NO 20773
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UniProt
- Q8WXI7
抗原
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