Recombinant ANO1 抗体
Quick Overview for Recombinant ANO1 抗体 (ABIN7543398)
抗原
See all ANO1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-DOG1 [19F2], Mouse IgG2b, kappa
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特异性
- The antibody is specific for DOG1. DOG1 is a calcium-activated chloride channel (CaCC) which plays a role in the transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles and it acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2b
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing mice with recombinant protein DOG1.
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亚型
- IgG2b kappa
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应用备注
- The antibody 19F2 and the commercial antibody SP31 were used to stain breast tissue and gastrointestinal tumor in immunohistochemistry. Results showed the antibody specificity is equivalent to the commercial antibody. Further, the staining intensity of the antibody 19F2 was higher than the commercial antibody (CN113045652A).
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
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别名
- DOG1
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背景
- Discovered On Gastrointestinal Stromal Tumors Protein 1, SP31, Anoctamin-1, Discovered on gastrointestinal stromal tumors protein 1, Oral cancer overexpressed protein 2, Transmembrane protein 16A, Tumor-amplified and overexpressed sequence 2, CGMCC NO. 20771
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UniProt
- Q5XXA6
抗原
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