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Recombinant ANO1 抗体

This anti-ANO1 antibody is a 兔 Chimeric antibody detecting ANO1 in IHC, WB 和 ELISA. Suitable for 人.
产品编号 ABIN7543397
发货至: 中国

Quick Overview for Recombinant ANO1 抗体 (ABIN7543397)

抗原

See all ANO1 抗体
ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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Chimeric

标记

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This ANO1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), ELISA

克隆位点

19F2
  • 原理

    Anti-DOG1 [19F2], Rabbit IgG, kappa

    特异性

    The antibody is specific for DOG1. DOG1 is a calcium-activated chloride channel (CaCC) which plays a role in the transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles and it acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2b

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by immunizing mice with recombinant protein DOG1.

    亚型

    IgG kappa
  • 应用备注

    The antibody 19F2 and the commercial antibody SP31 were used to stain breast tissue and gastrointestinal tumor in immunohistochemistry. Results showed the antibody specificity is equivalent to the commercial antibody. Further, the staining intensity of the antibody 19F2 was higher than the commercial antibody (CN113045652A).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

    别名

    DOG1

    背景

    Discovered On Gastrointestinal Stromal Tumors Protein 1, SP31, Anoctamin-1, Discovered on gastrointestinal stromal tumors protein 1, Oral cancer overexpressed protein 2, Transmembrane protein 16A, Tumor-amplified and overexpressed sequence 2, CGMCC NO. 20771

    UniProt

    Q5XXA6
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