Recombinant Dystroglycan 抗体
Quick Overview for Recombinant Dystroglycan 抗体 (ABIN7543383)
抗原
See all Dystroglycan (DAG1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Beta Dystroglycan [P38G1], Mouse IgG1, kappa
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特异性
- This antibody recognizes human and mouse beta dystroglycan (β-DAG). Beta-dystroglycan is a transmembrane protein that plays an important role in connecting the extracellular matrix to the cytoskeleton. It plays an important role in linking dystrophin to the laminin-binding alpha-dystroglycan. It acts as a cell adhesion receptor in both muscle and non-muscle tissues. It also functions in cell adhesion-mediated signaling and implicated in cell polarity.
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交叉反应
- 小鼠
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing BALB/c mice with a mixture of transfected HEK 293 cells expressing human and mouse beta-DAG.
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亚型
- IgG1 kappa
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anti-Dystroglycan 1 (DAG1) antibody
DAG1 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Dystroglycan 1 (DAG1) (AA 718-747), (C-Term) antibodyDAG1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33752 unconjugated
anti-Dystroglycan 1 (DAG1) (AA 28-406) antibodyDAG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystroglycan 1 (DAG1) (Internal Region) antibodyVerified DAG1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Dystroglycan 1 (DAG1) (AA 31-140) antibodyDAG1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A3 unconjugated
anti-Dystroglycan 1 (DAG1) (AA 726-744) antibodyDAG1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dystroglycan 1 (DAG1) (C-Term) antibodyDAG1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dystroglycan 1 (DAG1) (AA 721-770) antibodyDAG1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Dystroglycan 1 (DAG1) (AA 323-372) antibodyDAG1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, Bat, 小鸡, 猴, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Dystroglycan 1 (DAG1) (C-Term) antibodyDAG1 适用: 人 IHC, IHC (fro) 宿主: 小鼠 Monoclonal 43DAG1-8D5 unconjugated
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应用备注
- The binding specificity of this antibody to human and mouse beta dystroglycan expressed on the surface of CHO cells was confirmed using ELISA and flow cytometry. The binding affinity of the original IgG antibody to human beta dystroglycan was determined to be 941 pM. This antibody was used in combination with anti-Laminin antibody PL60B3 for the generation of a bispecific antibody (CN113651891).
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))
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别名
- Beta Dystroglycan
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背景
- Dystroglycan 1, Dag1, Beta-DG, β-DAG, BETA DAG, Dystroglycan, Dystrophin-associated glycoprotein 1, B-Dystroglycan, B Dystroglycan, Beta-dystroglycan, β dystroglycan, β-dystroglycan
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UniProt
- Q14118, Q62165
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途径
- Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
抗原
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