Recombinant LI Cadherin 抗体
Quick Overview for Recombinant LI Cadherin 抗体 (ABIN7543348)
抗原
See all LI Cadherin 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Cadherin 17 [D2111], Rabbit IgG, kappa
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特异性
- This antibody recognizes the human cadherin 17. Cadherins are calcium-dependent cell adhesion proteins. It is localized on the surfaces of epithelial cells in regions of cell-cell contact known as adherens junctions. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing GP64 transgenic mice with human cadherin 17.
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亚型
- IgG kappa
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应用备注
- The binding characterization and epitope mapping of this antibody was done using ELISA. This antibody was capable of binding Huh6 cell line (liver cancer) and AGS cells (gastric cancer) in flow cytometry. Cu64 labelled version of this antibody was also used in the PET imaging of AGS transplant mice (JP2017024991).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- LI Cadherin
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别名
- Cadherin 17
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背景
- Cadherin-17, CDH17, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin, LI-cadherin
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UniProt
- Q12864
抗原
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