电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Recombinant KRT17 抗体 (AA 410-432)

This anti-KRT17 antibody is a 小鼠 单克隆 antibody detecting KRT17 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7543317
发货至: 中国

Quick Overview for Recombinant KRT17 抗体 (AA 410-432) (ABIN7543317)

抗原

See all KRT17 抗体
KRT17 (Keratin 17 (KRT17))

抗体类型

Recombinant Antibody

适用

  • 146
  • 54
  • 31
  • 20
  • 15
  • 13
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 111
  • 48
  • 1
小鼠

克隆类型

  • 99
  • 60
  • 1
单克隆

标记

  • 77
  • 16
  • 9
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KRT17 antibody is un-conjugated

应用范围

  • 120
  • 67
  • 37
  • 33
  • 32
  • 27
  • 26
  • 26
  • 24
  • 16
  • 15
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Immunohistochemistry (IHC), ELISA

克隆位点

4D2
  • 抗原表位

    • 15
    • 15
    • 12
    • 12
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 410-432

    原理

    Anti-Cytokeratin 17 [4D2], Mouse IgG2a, kappa

    特异性

    This antibody is specific for amino acids 410-432 (TIVEEVQDGKVISSREQVHQTTR) of human cytokeratin 17. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin 17 regulates the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1).

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by immunizing female BALB/c mice with an immunogenic polypeptide containing amino acids 410-432 (TIVEEVQDGKVISSREQVHQTTR) of human cytokeratin 17 conjugated with KLH.

    亚型

    IgG2a kappa
  • 应用备注

    The binding characterization of this antibody to human cytokeratin 8 was done using ELISA. The affinity constant for the original IgG3 antibody was calculated to be 9.6 x 10^(8) M^(-1). This antibody is similar to commercially available anti-Cytokeratin 17 antibody E3 in staining various human tissues. This antibody can be used in the immunohistochemical analysis of esophageal squamous cell carcinoma (CN113278070).

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    KRT17 (Keratin 17 (KRT17))

    别名

    Cytokeratin 17

    背景

    CK17, CK-17, KRT17, K17, Keratin, type I cytoskeletal 17, Cytokeratin-17, Keratin-17, CGMCC NO 20762, E3

    UniProt

    Q04695
You are here:
Chat with us!