Recombinant KRT8 抗体
Quick Overview for Recombinant KRT8 抗体 (ABIN7543313)
抗原
See all KRT8 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Cytokeratin 8 [TS1], Mouse IgG1, kappa
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特异性
- This antibody binds a discontinuous epitope on helical 2B domain of the human cytokeratin 8 between amino acid residues 340-365 (QRGELAIKDANAKLSELEAALQRAKQ). Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Together with KRT19, cytokeratin 8 helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. Cytokeratin 8 is a serological tumor marker
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing BALB/c mice with purified human gastrointestinal tumor derived cytokeratin.
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亚型
- IgG1 kappa
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anti-Keratin 8 (KRT8) antibody
KRT8 适用: 人, 小鼠 WB, IHC, FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal M20 unconjugated
anti-Keratin 8 (KRT8) (AA 92-393) antibodyKRT8 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 8 (KRT8) (Ser726), (Ser731) antibodyKRT8 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 8 (KRT8) antibodyKRT8 适用: 人, 大鼠, 斑马鱼 WB, IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal H1 unconjugated
anti-Keratin 8 (KRT8) (pSer432) antibodyKRT8 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 8 (KRT8) (AA 91-381) antibodyKRT8 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Keratin 8 (KRT8) (AA 1-483) antibodyKRT8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 8 (KRT8) antibodyKRT8 适用: 人, Cow, 兔, Pig, 绵羊 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal B22-1 unconjugated
anti-Keratin 8 (KRT8) (AA 391-483) antibodyKRT8 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8A5D12 unconjugated
anti-Keratin 8 (KRT8) (Middle Region) antibodyKRT8 适用: 人, 大鼠, 小鼠, Cow, 兔, Pig, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- This antibody has specific reactivity for human cytokeratin 8. The binding characterization and epitope mapping of this antibody was done using ELISA (PMID: 9486565, 9892182). This antibody was also capable of immunoprecipitating human cytokeratin 8 from a sample. This antibody can be used in the identification of cytokeratin 8 in a western blot assay. This antibody was also used in the immunohistochemical staining of frozen sections of normal human adult tissues like skin, esophagus and liver (PMID: 2479674). This antibody is capable of binding cytokeratin 8 expressed on carcinomas in vivo. This antibody was used for the radio immunolocalization of cytokeratin 8 and radioimmunotherapy (PMID: 9892182, 7493362, 9406704).
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- KRT8 (Keratin 8 (KRT8))
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别名
- Cytokeratin 8
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背景
- CK8, CK-8, CK 8, KRT8, CYK8, Keratin type II cytoskeletal 8, Cytokeratin-8, Type-II keratin Kb8, TS 1, Mab 202
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UniProt
- P05787
抗原
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