Recombinant NCR1 抗体
Quick Overview for Recombinant NCR1 抗体 (ABIN7543305)
抗原
See all NCR1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-NKp46 [Bab281], Human IgG1, kappa
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特异性
- The antibody is specific for human NKp46. The antibody cross-reacts with macaque NK46 but does not cross-react with mouse NKp46. NKp46 is a receptor expressed by NK cells.
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交叉反应
- Macaque
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- The original antibody was generated by immunizing Balb/c mice with recombinant human NKp46 protein.
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亚型
- IgG1 kappa
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应用备注
- The antibody was used to immunoprecipitate NKp46 Molecules from NK and COS-7 cells (Pessino et al., 1998, PMID 9730896 and Cantoni et al. 1999, PMID: 10049942). NK cells were analyzed for NKp46 surface expression by immunofluorescence and Flow Cytometry analysis using the antibody (Sivori et al., 1999, PMID: 10359120). The antibody binding to NKp46 promoted an increase of cytolytic activity in NK cells (Sivori et al., 1997, PMID: 9314561 and Sivori et al., 1999, PMID: 10359120).
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说明
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This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
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别名
- NKp46
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背景
- Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, hNKp46, CD335
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UniProt
- O76036
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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