Recombinant CD2 抗体
Quick Overview for Recombinant CD2 抗体 (ABIN7543281)
抗原
See all CD2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Anti-CD2 [35.1], Mouse IgG2a, kappa
-
特异性
- This antibody recognizes an epitope on the extracellular domain of the human T cell surface protein Tp50 (CD2) between amino acid residues 39-50. The binding of this antibody does not inhibit the interaction between CD2 and CD58. CD2 is a glycoprotein belonging to the immunoglobulin superfamily. It acts as a specific marker for T lymphocytes, natural killer cells, thymic B cell subsets, and some antigen presenting cells. CD2 interacts with CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
-
产品特性
-
Original Species of Ab: Mouse
Original Format of Ab: IgG2a
-
纯化方法
- Protein A affinity purified
-
免疫原
- The original antibody was generated by immunizing mice with human T lymphocytes that had been activated with phorbol myristic acid (PMA).
-
亚型
- IgG2a kappa
-
-
anti-CD2 (CD2) (AA 25-140) antibody
CD2 适用: 小鼠 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 3D1E3 unconjugated
anti-CD2 (CD2) (N-Term) antibodyCD2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) (AA 1-351) antibodyCD2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 适用: 人 FACS, IF, WB, Func 宿主: 小鼠 Monoclonal 1E7E8-G4 unconjugated
anti-CD2 (CD2) antibody (FITC)CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal LT2 FITC
anti-CD2 (CD2) antibody (PE)CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal LT2 PE
anti-CD2 (CD2) antibody (FITC)GMP Grade CD2 适用: 人 FACS 宿主: 小鼠 Monoclonal OKT11 FITC
anti-CD2 (CD2) (AA 25-209) antibodyCD2 适用: 人 IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) (AA 1-351) antibodyCD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD2 (CD2) antibodyCD2 适用: 人, Pig, Non-Human Primate FACS, IF 宿主: 小鼠 Monoclonal LFA2-600 unconjugated
-
-
应用备注
- This antibody inhibits T cell proliferative responses and cytotoxicity, but does not inhibit antibody mediated cellular cytotoxicity. This antibody was used in the generation of CD2 targeting ricin A chain-containing immunotoxins (PMID: 2461993). This antibody is capable of immunoprecipitating CD2 antigen form cell lysates (PMID: 8557753). This antibody was also used for the cell cycle analysis of cells along with other antibodies like anti-CD3, anti-CD4, and anti-CD8 using flow cytometry (PMID: 9881968).
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % Proclin 300.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
-
- CD2
-
别名
- CD2
-
背景
- LFA-2, LFA-3 receptor, SRBC, Rosette receptor, T-cell surface antigen CD2, Erythrocyte receptor, T-cell surface antigen T11/Leu-5
-
UniProt
- P06729
抗原
-
