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Recombinant MBP 抗体 (AA 78-88, AA 80-89)

The 小鼠 单克隆 anti-MBP antibody is suitable to detect MBP in samples from 人 和 Cow. It has been validated for ELISA 和 RIA.
产品编号 ABIN7543257
发货至: 中国
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Quick Overview for Recombinant MBP 抗体 (AA 78-88, AA 80-89) (ABIN7543257)

抗原

See all MBP 抗体
MBP (Myelin Basic Protein (MBP))

抗体类型

Recombinant Antibody

适用

  • 168
  • 42
  • 40
  • 24
  • 13
  • 11
  • 9
  • 8
  • 7
  • 7
  • 6
  • 5
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
人, Cow

宿主

  • 112
  • 46
  • 12
  • 12
  • 2
  • 1
小鼠

克隆类型

  • 92
  • 90
  • 1
单克隆

标记

  • 120
  • 11
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MBP antibody is un-conjugated

应用范围

  • 131
  • 88
  • 50
  • 38
  • 30
  • 24
  • 11
  • 11
  • 8
  • 7
  • 6
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
ELISA, Radioimmunoassay (RIA)

克隆位点

845D3
  • 抗原表位

    • 20
    • 10
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 78-88, AA 80-89

    原理

    Anti-Myelin basic protein [845D3], Mouse IgG1, kappa

    特异性

    This antibody binds human myelin basic protein (MBP), amino acid residues 80-89 (QDENPVVHF). This antibody also cross reacts with bovine MBP comprising amino acids 78-88. The MBP isoforms 4 and 14 along with PLP are most abundant protein components of the myelin membrane in the CNS. The smaller isoforms are believed to have an important role in remyelination of denuded axons in multiple sclerosis.

    Application Notes original Clone: The epitope mapping of this antibody was done using solid phase radioimmunoassay (PMID: 2419434). This antibody can be used in the dection of MBP in a sample using ELISA (PMID: 2466871).

    交叉反应

    Cow

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by hyperimmunization of BALB/c mice with human MBP peptide comprising amino acids from 80-89.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    OriginalSpeciesName: Mouse

    OriginalFormat: IgG1

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    MBP (Myelin Basic Protein (MBP))

    别名

    Myelin basic protein

    背景

    MBP, Myelin A1 protein, Myelin membrane encephalitogenic protein, 84-5D3

    UniProt

    P02686
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