Recombinant CD19 抗体
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北京 101111
Quick Overview for Recombinant CD19 抗体 (ABIN7543176)
抗原
See all CD19 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD19 [MB19-1], Mouse IgG1, kappa
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特异性
- This antibody recognizes murine MB19-1 (CD19), a transmembrane protein present in B lymphocytes that regulates its activation. It is required for proper differentiation of B-1 cells.
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交叉反应
- 犬
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgA
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was raised by immunising CD19-deficient mice with a cell line of mCD19+ mouse pre-B cells.
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亚型
- IgG1 kappa
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应用备注
- This clone can be used to detect and analyze the presence of the CD19 transmembrane protein. The specificity towards the protein has been confirmed using ELISA and immunofluorescence (Sato et al., 1996, PMID: 8906812). Additionally, the MB19-1 antibody has been used in several flow cytometry assays. One group used this antibody to determine the differences in CD19 distribution between cells of young and old mice (Yamamoto et al., 2018, PMID: 29625072). Another group used it to differentiate eosinophils from other leukocytes (Vanella et al., 2017, PMID: 27043413). A final group used flow cytometry to determine the fraction of B cells cells in a sample with this antibody (Bedaret et al., 2009, PMID: 19907079).
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说明
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This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgA format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD19 (CD19 Molecule (CD19))
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别名
- CD19
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背景
- B-lymphocyte antigen CD19, Differentiation antigen CD19, B-lymphocyte surface antigen B4, B4, CD19 Molecule, CD19 antigen
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UniProt
- P25918
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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