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Recombinant Fc gamma RII (CD32) 抗体

This anti- antibody is a 兔 Chimeric antibody detecting in FACS, IHC, ELISA, IF 和 BR. Suitable for 人.
产品编号 ABIN7543154
发货至: 中国

Quick Overview for Recombinant Fc gamma RII (CD32) 抗体 (ABIN7543154)

抗原

See all Fc gamma RII (CD32) 抗体
Fc gamma RII (CD32)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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Chimeric

标记

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非结合性

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Blocking Reagent (BR)

克隆位点

MDE-9
  • 原理

    Anti-CD32 [MDE-9], Rabbit IgG, kappa

    特异性

    This antibody recognizes and binds Fc-gamma receptor IIa (FcγRIIa) or CD32a and, more particularly, the FcγRIIa-H131 allotype.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    The original antibody was generated by immunizing Human Ig-Tg (Co7) mice with FcgammaRIIa-H131 conjugated to human serum albumin in complete Freund's adjuvant.

    亚型

    IgG kappa
  • 应用备注

    MDE-9 was able to detect FcgammaRIIa-H131 in both flow cytometry and immunohistochemistry. MDE-9 bound FcgRIIa-H131 on cell lines expressing FcgRIIaH131, as well as on peripheral blood monocytic cells and PMN in immunofluorescence assays. MDE-9 was used to develop an FcgammaRIIa allotyping method based on flow cytometry. The results of flow cytometric FcgammaRIIa allotyping correlated completely with PCR genotyping. This novel allotyping assay can facilitate the screening of patients in a routine diagnostic setting. A combination of MDE-9 and mAb 41H16 can be used in FcgammaRIIa-H/H131 homozygous individuals to detect FcgammaRIIa and FcgammaRIIb surface expression on monocytes (PMID: 15604023).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    Fc gamma RII (CD32)

    别名

    CD32

    背景

    CDw32, Fc-gamma RII-a, FcγRIIa, FcγRII, FcRII-a, FCGR2A, FcgammaRIIa-H131, IgG Fc receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-a

    UniProt

    P12318
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