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Recombinant Desmoglein 3 抗体

This 兔 Chimeric anti-Desmoglein 3 antibody (Clone 5G11) specifically detects Desmoglein 3 in WB, IHC, IF, FACS, IP 和 DB. The antibody is reactive with 人 samples.
产品编号 ABIN7543134
发货至: 中国
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Quick Overview for Recombinant Desmoglein 3 抗体 (ABIN7543134)

抗原

See all Desmoglein 3 (DSG3) 抗体
Desmoglein 3 (DSG3)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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Chimeric

标记

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This Desmoglein 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Dot Blot (DB)

克隆位点

5G11
  • 原理

    Anti-desmoglein-3 [5G11], Rabbit IgG, kappa

    特异性

    This antibody recognizes desmoglein 3. It does not cross-react with desmoglein 1 or desmoglein 2. Desmoglein-3 is a calcium binding membrane protein that is localized in desmosome cellular junctions and interacts with plaque proteins and intermediate filaments at cell-cell adhesion points.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was raised by immunizing Balb/c mice with a recombinant protein corresponding to human desmoglein-3.

    亚型

    IgG kappa
  • 应用备注

    This antibody can be used for detection and analysis of desmoglein-3 via various methods. For instance, 5G11 was utilized todetect desmoglein-3 in human scalp hair follicles and epidermal inclusions via immunohistochemistry (Wu et al., 2003). Another group successfully used this antibody to identify desmoglein-3 via Western blot (Mao et al., 2017, pmid: 28469076). The antibody 5G11 was also used to detect DSG3 in cells via immunofluorescence (Chen et al., 2013, pmid: 23737966).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    Desmoglein 3 (DSG3)

    别名

    desmoglein-3

    背景

    PVA, Cadherin family member 6, desmoglein 3, 130 kDa pemphigus vulgaris antigen, DSG3

    UniProt

    P32926
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