Recombinant Desmoglein 3 抗体
Quick Overview for Recombinant Desmoglein 3 抗体 (ABIN7543134)
抗原
See all Desmoglein 3 (DSG3) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-desmoglein-3 [5G11], Rabbit IgG, kappa
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特异性
- This antibody recognizes desmoglein 3. It does not cross-react with desmoglein 1 or desmoglein 2. Desmoglein-3 is a calcium binding membrane protein that is localized in desmosome cellular junctions and interacts with plaque proteins and intermediate filaments at cell-cell adhesion points.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was raised by immunizing Balb/c mice with a recombinant protein corresponding to human desmoglein-3.
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亚型
- IgG kappa
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应用备注
- This antibody can be used for detection and analysis of desmoglein-3 via various methods. For instance, 5G11 was utilized todetect desmoglein-3 in human scalp hair follicles and epidermal inclusions via immunohistochemistry (Wu et al., 2003). Another group successfully used this antibody to identify desmoglein-3 via Western blot (Mao et al., 2017, pmid: 28469076). The antibody 5G11 was also used to detect DSG3 in cells via immunofluorescence (Chen et al., 2013, pmid: 23737966).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Desmoglein 3 (DSG3)
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别名
- desmoglein-3
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背景
- PVA, Cadherin family member 6, desmoglein 3, 130 kDa pemphigus vulgaris antigen, DSG3
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UniProt
- P32926
抗原
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