Recombinant Desmocollin 2+3 (Extracellular Domain) 抗体
This anti- antibody is a 兔 Chimeric antibody detecting in IF, FACS, IHC 和 IP. Suitable for 人.
Quick Overview for Recombinant Desmocollin 2+3 (Extracellular Domain) 抗体 (ABIN7543132)
抗原
Desmocollin 2+3
抗体类型
Recombinant Antibody
适用
人
宿主
兔
克隆类型
Chimeric
标记
非结合性
应用范围
Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
克隆位点
7G6
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抗原表位
- Extracellular Domain
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原理
- Anti-desmocollin-2/3 [7G6], Rabbit IgG, kappa
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特异性
- This antibody recognizes desmocollin-2 (also known as Desmocollin-3). Desmocollins (next to desmogleins) are the main desmosomal transmembrane proteins.The expression of desmocollin-2 varies in the basal and suprabasal layers.
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交叉反应
- 小鼠, 大鼠
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was raised by immunizing mice with a MBP-tagged recombinant protein corresponding to the extracellular domain of human Desmocollin-2.
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亚型
- IgG kappa
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anti-Desmocollin 2+3 (Extracellular Domain) antibody
适用: 人, 小鼠, 大鼠 IF, WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 7G6 unconjugated
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应用备注
- The antibody 7G6 is recommended for the detection and analysis of desmocollin-2 (desmocollin-3) via various methods, such as immunohistochemistry, Western blot and others. For instance, the antibody was used to label desmocollin-2 in primary human keratinocytes via immunohistochemistry (Franke et al., 2006). Similarly, another group detected desmocollin-2 in A431 cells (Wahl et al., 2005). The antibody 7G6 was also utilized in the assessment of expression levels of desmocollin-2 in SHEEC and KYSE510 cells via Western blot (Fang et al., 2014).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Desmocollin 2+3
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别名
- desmocollin-2/3
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背景
- Desmocollin, Desmocollin-2, Cadherin family member 2, Desmocollin-3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, Cadherin family member 3, Dsc2/3, Dsc2, Dsc3, DG2, DG3
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UniProt
- Q02487
抗原
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