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Recombinant Desmocollin 2+3 (Extracellular Domain) 抗体

适用: 人 IF, FACS, IHC, IP 宿主: 小鼠 Monoclonal 7G6 unconjugated Recombinant Antibody
产品编号 ABIN7543131
发货至: 中国
  • 抗原
    Desmocollin 2+3
    抗体类型
    Recombinant Antibody
    抗原表位
    Extracellular Domain
    适用
    • 11
    • 9
    • 9
    宿主
    • 10
    • 1
    小鼠
    克隆类型
    • 10
    • 1
    单克隆
    标记
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 11
    • 10
    • 10
    • 8
    • 2
    • 2
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    原理
    Anti-desmocollin-2/3 [7G6], Mouse IgG1, kappa
    特异性
    This antibody recognizes desmocollin-2 (also known as Desmocollin-3). Desmocollins (next to desmogleins) are the main desmosomal transmembrane proteins.The expression of desmocollin-2 varies in the basal and suprabasal layers.
    交叉反应
    小鼠, 大鼠
    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法
    Protein A affinity purified
    免疫原
    This antibody was raised by immunizing mice with a MBP-tagged recombinant protein corresponding to the extracellular domain of human Desmocollin-2.
    克隆位点
    7G6
    亚型
    IgG1 kappa
  • 应用备注
    The antibody 7G6 is recommended for the detection and analysis of desmocollin-2 (desmocollin-3) via various methods, such as immunohistochemistry, Western blot and others. For instance, the antibody was used to label desmocollin-2 in primary human keratinocytes via immunohistochemistry (Franke et al., 2006). Similarly, another group detected desmocollin-2 in A431 cells (Wahl et al., 2005). The antibody 7G6 was also utilized in the assessment of expression levels of desmocollin-2 in SHEEC and KYSE510 cells via Western blot (Fang et al., 2014).
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    Desmocollin 2+3
    别名
    desmocollin-2/3
    背景
    Desmocollin, Desmocollin-2, Cadherin family member 2, Desmocollin-3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, Cadherin family member 3, Dsc2/3, Dsc2, Dsc3, DG2, DG3
    UniProt
    Q02487
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