Recombinant GRIN2B 抗体
Quick Overview for Recombinant GRIN2B 抗体 (ABIN7543081)
抗原
See all GRIN2B 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-NMDA Receptor [17], Rabbit IgG, kappa
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特异性
- Reacts specifically with rat GluN2B ATD.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG
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纯化方法
- Protein A affinity purified
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免疫原
- Monoclonal antibodies that bind rat GluN2B ATD were obtained by immunizing mice with the purified intact GluN1-GluN2B NMDA receptors. IgGs were purified from hybridoma cell culture supernatant by Protein-A Sepharose. Fab fragments have been prepared by papain proteolysis followed by re-chromatographing onto Protein-A Sepharose to remove Fc.
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亚型
- IgG kappa
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应用备注
- This antibody has been used for the crystallisation of the NMDA receptor in the absence of an allosteric inhibitor at 2.9A (Tajima 2016).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
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别名
- Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B
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背景
- NMDAR, NMDA-R, Glutamate receptor
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UniProt
- Q00960
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途径
- Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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