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Recombinant CD43 抗体

The 小鼠 单克隆 anti-CD43 antibody (Clone OX-56) (ABIN7543057) specifically detects CD43 in WB 和 IP. The antibody is reactive with 大鼠 samples.
产品编号 ABIN7543057
发货至: 中国
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Quick Overview for Recombinant CD43 抗体 (ABIN7543057)

抗原

See all CD43 (SPN) 抗体
CD43 (SPN) (Sialophorin (SPN))

抗体类型

Recombinant Antibody

适用

  • 150
  • 16
  • 16
  • 1
  • 1
大鼠

宿主

  • 85
  • 84
  • 7
  • 1
小鼠

克隆类型

  • 107
  • 66
  • 4
单克隆

标记

  • 81
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  • 9
  • 6
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This CD43 antibody is un-conjugated

应用范围

  • 113
  • 100
  • 78
  • 53
  • 44
  • 30
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  • 6
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Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

OX-56
  • 原理

    Anti-CD43 [OX-56], Mouse IgG2b, kappa

    特异性

    OX-56 binds specifically to CD43 and binding is not affected by CD43 glycosylation. OX-56 reacts with most thymocytes and T lymphocytes in the lymph node cell population. This antibody also binds to pre-B cells and can detect CD43 at low levels on B cells. CD43 plays a role in the physicochemical properties of the T-cell surface and in lectin binding. CD43 is a major cell-surface sialoglycoprotein - also found on neutrophils, bone marrow stem cells, B-lineage cells after activation of thymocytes and T lymphocytes but is not expressed on resting B lymphocytes. The protein presents carbohydrate ligands to selectins and Is a counter-receptor for SN/Siglec-1. During T-cell activation it is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2b

    纯化方法

    Protein A affinity purified

    免疫原

    OX-56 was prepared by immunizing BALB/c mice with activated rat T lymphocytes.

    亚型

    IgG2b kappa
  • 应用备注

    OX-56 has been used in the purification of rat leukosialin by immunoaffinty chromatography (Willis et al. 1987) as well as in WB.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD43 (SPN) (Sialophorin (SPN))

    别名

    CD43

    背景

    Leukosialin, OX56, MRC OX-56, MRC OX56, sialophorin

    UniProt

    P13838

    途径

    Regulation of Leukocyte Mediated Immunity
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