Recombinant SIRPG 抗体
Quick Overview for Recombinant SIRPG 抗体 (ABIN7543055)
抗原
See all SIRPG 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-SIRP g [OX-119], Rabbit IgG, kappa
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特异性
- Hybridoma supernatants were initially screened by ELISA, using SIRPg-CD4, human SIRPa-Fc, human SIRPb-Fc or CD4 to eliminate hybridomas with cross-reactivity to rat CD4, human SIRPa, and SIRPb. There is some marginal binding of OX-119 to SIRPb transfected 293T cells. SIRPg binds CD47. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells..
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- OX-119 was prepared by immunizing BALB/c mice with a chimeric protein made up of human SIRPg and a leader peptide of rat CD4 domain (SIRPg-CD4 ).
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亚型
- IgG kappa
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anti-Signal-Regulatory Protein gamma (SIRPG) (AA 29-360) antibody
SIRPG 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4F8C10 unconjugated
anti-Signal-Regulatory Protein gamma (SIRPG) (AA 29-360) antibodySIRPG 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7H3A2 unconjugated
anti-Signal-Regulatory Protein gamma (SIRPG) (AA 111-372) antibodySIRPG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein gamma (SIRPG) antibodySIRPG 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal OX-119 unconjugated
anti-Signal-Regulatory Protein gamma (SIRPG) antibody (PE)SIRPG 适用: 人 FACS 宿主: 小鼠 Monoclonal OX-119 PE
anti-Signal-Regulatory Protein gamma (SIRPG) (AA 1-387) antibodySIRPG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Signal-Regulatory Protein gamma (SIRPG) (C-Term) antibodySIRPG 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein gamma (SIRPG) (AA 109-158) antibodySIRPG 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein gamma (SIRPG) antibodySIRPG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- OX-119 is able to perform staining of peripheral blood myeloid cells (PBMCs) and block SIRPg-mediated apoptosis. OX-119 can also be used in IP, FC and ELISA.
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- SIRPG (Signal-Regulatory Protein gamma (SIRPG))
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别名
- SIRP g
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背景
- CD172g, OX119, MRC OX-119, MRC OX119, SIRP-g, SIRPg, SIRP gamma, SIRP-gamma, CD172 antigen-like family member B, signal-regulatory protein beta, CD172-g
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UniProt
- Q9P1W8
抗原
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